View Full Version : PI3K target

8th September 2002, 01:37 PM
have a PI3K on one machien and PTEN on the other...

the former is much slower (about 3.5 times) than PTEN :(

Anyone else got this one?


8th September 2002, 02:10 PM
Out of 1283 Candidates, 601 have been the PI3K. Since this is a straight scoring system 20:1, one would think that they would size the work to be similar.

8th September 2002, 02:41 PM
Right, well, for the PI3K the avg docking time was 1:58 while now, back on the PTEN its 0:37, quite some difference..


8th September 2002, 02:47 PM
Just checked 2 of my boxen......

1.53@1.53 running a PTEN :31 docking time
1.53@1.674 running a PI3K :36 docking time

edit...must be a factor of the actual protein.......my slowest 1.53 (pcchips mobo) which is 20% slower on DF is running the PTEN at :19 docking .....

Seems to be a modest difference here.:confused:

8th September 2002, 03:49 PM
Seems there are many many different candidates for each target and all candidates vary in size and complexity.

The targets, PTEN and PI3K dont vary. This is startign to make sense :)